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. Author manuscript; available in PMC: 2018 Jun 23.
Published in final edited form as: ACS Comb Sci. 2015 Sep 17;17(10):641–652. doi: 10.1021/acscombsci.5b00101

Figure 5.

Figure 5

Inhibition of wild-type HCV infection in human hepatocytes by selected analogs. Huh7.5.1 cells were seeded in 12-well plates (105 cells/well) and cultured overnight. HCVcc was used to infect the cells with the treatment of compounds at 10 µM. Virus-containing medium was removed after 4 h incubation, and compound treatment was added back, followed by incubation for an additional 48 h. Intracellular and extracellular viral RNA levels were evaluated by quantitative real-time PCR. The results shown are the means of three replicates ± SE. Cyclosporin A at 10 µM was used as a positive control.