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HCV Inhibition and Cytotoxicity of 2-Aryl-Containing Benzofuran Analogs
| Cmpd |
|
HCV-Luc EC50 (µM) |
ATPlite CC50 (µM) |
Selective Index (SI) |
||
|---|---|---|---|---|---|---|
| R1 | R2 | R3 | ||||
| 4{1} |
|
|
|
>31.6 | >100 | N.A. |
| 4{2} |
|
|
|
12.00 | >100 | >8 |
| 4{3} |
|
|
|
3.59 | 38.10 | 11 |
| 4{4} |
|
|
|
2.34 | >100 | >43 |
| 4{5} |
|
|
|
1.84 | >100 | >54 |
