Table 2.
iGFR | CKiDSCr-Cys | CKiDSCr | CKD-EPISCr | CKD-EPICys | CKD-EPISCr-Cys | |
---|---|---|---|---|---|---|
Mean, ml/min|1.73m2 | 49.2 | 50.7 | 43.6 | 57.4 | 51.8 | 52.4 |
Standard deviation | 22.5 | 21.1 | 20.2 | 30.8 | 29.4 | 29.2 |
Average bias, ml/min|1.73m2 (95%CI) |
0 |
+1.5 (+0.6, +2.5) |
−5.6 (−7.1, −4.2) |
+8.2 (+6.7, +9.7) |
+2.7 (+1.3, +4.0) |
+3.3 (+2.1, +4.4) |
Ratio of SDs (95%CI) |
1 |
0.94 (0.89, 0.99) |
0.89 (0.81, 0.97) |
1.39 (1.28, 1.50) |
1.32 (1.24, 1.40) |
1.31 (1.24, 1.38) |
Correlation | 1 | 0.94 | 0.89 | 0.91 | 0.90 | 0.94 |
RMSE, ml/min|1.73m2 | 0 | 7.1 | 9.2 | 13.0 | 12.3 | 10.0 |
% within 30% of iGFR | Reference | 90% | 71% | 66% | 74% | 76% |
Abbreviations: Iohexol GFR (iGFR); CKiD eGFR equation based on serum creatinine and cystatin C (CKiDSCr-Cys); CKiD eGFR equation based on serum creatinine only (CKiDSCr); CKD-EPI eGFR equation based on serum creatinine only (CKD-EPISCr), cystatin C only (CKD-EPICys), and serum creatinine and cystatin C (CKD-EPISCr-Cys); standard deviations (SDs); root mean square error (RMSE).