Table 13.
Cytokine production by spleen cells from male and female rats of feeding trial E incubated with concanavalin A or Cry1Ab
| Parameter | Male rats | Female rats | ||||
|---|---|---|---|---|---|---|
| Control | 11% GMO | 33% GMO | Control | 11% GMO | 33% GMO | |
| Interleukin-2 (pg/ml; Con A) | 7022 ± 1105c | 6291 ± 1373b | 6786 ± 1327c | 5096 ± 982 | 5809 ± 933 | 6456 ± 861a |
| Interleukin-4 (pg/ml; Con A) | 12.70 ± 4.94 | 9.64 ± 4.35 | 7.55 ± 1.06 | 12.95 ± 5.10 | 17.31 ± 10.32 | 42.90 ± 40.33 |
| Interleukin-10 (pg/ml; Con A) | 3787 ± 2771 | 2873 ± 1603 | 3273 ± 1692 | 2067 ± 1670 | 3666 ± 3053 | 2204 ± 1461 |
| Interleukin-17A (pg/ml; Con A) | 268 ± 157 | 239 ± 96 | 255 ± 148 | 311 ± 241 | 321 ± 159 | 370 ± 148 |
| Tumour necrosis factor-α (pg/ml Con A) | 62.23 ± 14.10 | 52.51 ± 12.51 | 69.66 ± 20.32 | 43.51 ± 10.38 | 47.69 ± 8.36a | 57.14 ± 16.68 |
| Interleukin-10 (pg/ml; Cry1Ab) | 310 ± 45 | 278 ± 67 | 392 ± 129 | 360 ± 187a | 329 ± 69 | 537 ± 159 |
Spleen cells were incubated for 72 h with concanavalin A (Con A) or for 144 h with Cry1Ab. The table lists the amount of cytokines released into the cell culture medium, expressed as cage mean ± SD (5 cages, n = 10 rats, if not otherwise stated; four cages in the case of n = 7 rats)
an = 9
bn = 8
cn = 7