TABLE II.

Table of Cytokines, by Smoking Status.

	Never Smokers (N = 7)		Former/Current Smokers (N = 21)
Cytokine	Geo Mean	95% CI	Geo Mean	95% CI	P Value*
IL-6	22565	160369, 317529	20459	16454, 25437	0.633
IL-8	7611.4	5003.5, 11578.6	5946.7	3966.1, 8916.4	0.560
IL-1 beta	63.23	8.59, 465.20	67,88	23.07, 199.73	0.853
TGF_b1	693.1	307.3, 1563.3	234.0	123.5, 443.2	0.090
TNF alpha	6.35	1.52, 26.48	5.17	2.67, 10.03	0.652
EGF	192.6	72.8, 509.9	44.72	24.21, 82.61	0.030*
FGF	999.2	387.1, 2579.5	711.7	393.1, 1288.9	0.524
MMP-1	4564.1	1287.1, 16184.3	5837.4	2632.8, 12942.4	0.958
MMP-2	95649	62071, 147391	100915	78017, 130534	0.874
MMP-9	445730	384429, 516807	388525	345168, 437329	0.100
VEGF-A	7372.3	4810.3, 11298.8	7995.6	5445.2, 11740.5	0.710
PLGF	66.45	26.62, 165.86	173.42	85.9, 350.0	0.124
sFLT-1	3.22	1.20, 8.63	0.71	0.36, 1.39	0.011*
CRP	1289.6	160.9, 10334.9	3031.6	1391.6, 6604.6	0.396

All cytokines reported in pg/mL with the exception of CRP, reported in ng/mL.

^*Highlights statistical significance from the Wilcoxon rank sum test.

bFGF = basic fibroblastic growth factor; CI = confidence interval; Geo Mean = geometric mean; MMP = matrix metalloproteinases.