Table 3.

Efficacy analysis

Efficacy variable	Study group (n = 125)	Control group (n = 138)	p-value
AUC of BT change at 6 h after administration-and-time relationship	5.98 ± 3.87	5.78 ± 4.01	0.683
BT reduction at 4 h after administration (°C)	0.97 ± 0.90	1.16 ± 0.92	0.09
Maximum value of BT reduction during the 6 h after administration (°C)	1.63 ± 0.66	1.64 ± 0.70	0.855
Number of patients whose BT normalized (< 37.0 °C) at 6 h after administration, n (%)	26 (20.8)	23 (16.7)	0.390
Time point when BT first reached < 37.0 °C, hour	1.73 ± 1.29	2.13 ± 1.06	0.064

Results are presented as mean ± standard deviation or as a percentage (%)

BT Body Temperature

AUC Area Under the Curve