Table 2.

Comparison of quantified neurotoxicity

Heterocyclic amine	Subclass	Threshold for detectable selective DA neurotoxicity	DA neuron loss at 1 µM
IQ	Aminoimidazoaazarene	5 µM	Not significant
MeIQ	Aminoimidazoaazarene	200 nM	25%
MeIQx	Aminoimidazoaazarene	1 µM	17%
4,8-DiMeIQx	Aminoimidazoaazarene	100 nM	26%
PhIP	Aminoimidazoaazarene	1 µM	19%
Harmane	β-carboline	200 nM	21%
Norharmane	β-carboline	100 nM	20%
AαC	α-carboline	1 µM	27%