Table 2.
Primary Analysis | Sensitivity Analysis | |||||
---|---|---|---|---|---|---|
Hypoglycemia N (%) | Hyperglycemia N (%) | p-value | Hypoglycemia N (%) | Hyperglycemia N (%) | p-value | |
Insulin | 3509 (54.7) | 5835 (84.9) | <0.001 | 3065 (47.7) | 5524 (80.4) | <0.001 |
Metformin | 1959 (30.5) | 1347 (19.6) | <0.001 | 1470 (22.9) | 903 (13.1) | <0.001 |
Sulfonylurea | 2328 (36.3) | 777 (11.3) | <0.001 | 1408 (21.9) | 489 (7.1) | <0.001 |
GLP-1 receptor agonist | 129 (2.0) | 104 (1.5) | 0.03 | 90 (1.4) | 51 (0.7) | <0.001 |
DPP-4 inhibitor | 569 (8.9) | 317 (4.6) | <0.001 | 416 (6.5) | 198 (2.9) | <0.001 |
SGLT2 inhibitor | 13 (0.2) | 32 (0.5) | 0.009 | <11* | 14 (0.2) | 0.52 |
Other | 620 (9.7) | 303 (4.4) | <0.001 | 391 (6.1) | 166 (2.4) | <0.001 |
No medications | 984 (15.3) | 706 (10.3) | <0.001 | 1671 (26.0) | 1052 (15.3) | <0.001 |
Data with cells containing ≤11 patients is suppressed in order to maintain strict patient deidentification.