FIGURE 5.

Semi-quantification of NF-L, INA, NF-M, and NF-H immunofluorescence intensity in the model of fMCAO. Coronal mouse brain sections labeled with NF-L (red) and NF-H (green) illustrate the predefined ROIs in the cortex (A), as well as the peripheral (P), transitional (T), and central (C) areas of the striatum (B). Semi-quantification reveals a significant increase of NF-L immunoreactivity, as well as a significant decrease of INA immunoreactivity in the ischemic tissue of the neocortex (A) and striatum (B). NF-M immunoreactivity is significantly decreased in the ischemic neocortex, while NF-H immunoreactivity is not significantly altered (A). NF-M and NF-H show a trend towards decreased immunoreactivities in the ischemic striatum (B). Data are given as mean values; error bars indicate SEM. ^∗p < 0.05; n = 5.