Table 2.

Age-standardized prevalence of baseline comorbidities in adult patients with psoriasis by severity of the disease

Comorbidities	Mild psoriasisa			Moderate-to-severe psoriasisb			Severe psoriasisc
	No.	%	95% CI	No.	%	95% CI	No.	%	95% CI
	70796			11919			2147
Cardiovascular diseases
Myocardial infarction	2070	2.50	2.39–2.62	271	2.30	2.03–2.58	27	1.82	1.29–2.47
Angina pectoris	2112	2.55	2.43–2.67	307	2.63	2.36–2.94	43	2.24	1.65–2.95
Peripheral arterial diseased	1449	1.75	1.66–1.85	213	1.77	1.54–2.02	21	3.26	2.55–4.10
Atrial fibrillation	2454	3.13	3.00–3.26	330	3.16	2.85–3.49	44	2.19	1.61–2.90
Heart failure and hypertensive diseases	2913	3.74	3.60–3.87	395	3.74	3.40–4.09	59	5.08	4.19–6.09
Essential hypertensiond	25075	29.88	29.54–30.21	4183	32.62	31.77–33.47	665	36.47	34.42–38.55
Cerebrovascular diseases
Stroke	1918	2.42	2.31–2.53	238	2.16	1.90–2.43	21	1.07	0.68–1.60
Transient ischemic attack	612	0.76	0.70–0.83	81	0.75	0.60–0.92	9	0.51	0.26–0.91
Metabolic diseases
Diabetesd	6288	7.60	7.41–7.80	1018	8.00	7.52–8.51	162	10.67	9.39–12.05
Treatment with statins	11804	13.50	13.25–13.76	1814	13.61	13.00–14.23	241	16.44	14.90–18.08
Obesity	1419	1.97	1.87–2.07	294	2.40	2.13–2.69	56	1.96	1.41–2.64
Other disease
Chronic obstructive pulmonary disease	2715	3.58	3.45–3.72	520	4.60	4.24–5.00	107	4.70	3.85–5.69

Notes:

^aTopical treatment with calcipotriol or calcipotriol combinations.

^bNon-biological systemic treatment with methotrexate, cyclosporine, acitretin and phototherapy.

^cBiological treatment with adalimumab, etanercept, infliximab, efalizumab, ustekinumab, certolizumab, golimumab.

^dData obtained from both Swedish National Patient Register and Prescribed Drug Register (Table S3).