Table 1.
Baseline demographics, medications, ECG and echocardiographic findings according to frequent idiopathic premature ventricular complex >10%.
| Variables | Control group (n = 170) | PVC > 10% group (n = 203) | P-value |
|---|---|---|---|
| Age (years) | 57.6 ± 16.4 | 61.0 ± 15.2 | 0.042 |
| Gender (Male, %) | 80 (47.3) | 88 (43.3) | 0.465 |
| DM (%) | 34 (20.0) | 34 (17.5) | 0.591 |
| HTN (%) | 52 (30.6) | 55 (28.4) | 0.647 |
| CAD (%) | 21 (12.4) | 22 (11.3) | 0.871 |
| PCI (%) | 8 (4.7) | 16 (8.2) | 0.207 |
| CABG (%) | 1 (0.6) | 0 (0) | 0.467 |
| Medication | |||
| Anti-arrhythmics (%) | |||
| Amiodarone (%) | 0 (0) | 15 (7.7) | <0.001 |
| Propafenone (%) | 0 (0) | 2 (1.0) | 0.501 |
| Digoxin (%) | 8 (4.8) | 10 (5.2) | 0.484 |
| Beta-blocker (%) | 14 (8.2) | 104 (53.6) | <0.001 |
| CCB (%) | 34 (20) | 42 (21.6) | 0.989 |
| ARB & ACEi (%) | 28 (16.4) | 33 (17.0) | 0.896 |
| Statins (%) | 64 (37.6) | 80 (39.4) | 0.464 |
| Aspirin (%) | 43 (25.3) | 50 (24.6) | 0.268 |
| Clopidogrel | 20 (12.0) | 26 (13.4) | 0.118 |
| VKA | 19 (11.2) | 19 (9.8) | 0.732 |
| Laboratory findings | |||
| WBC (103/uL) | 7.8 ± 3.0 | 7.4 ± 2.7 | 0.598 |
| Creatinine (mg/dL) | 1.3 ± 0.9 | 1.2 ± 0.6 | 0.436 |
| TSH (mg/dL) | 2.8 ± 1.7 | 2.7 ± 1.6 | 0.898 |
| fT4 | 1.2 ± 0.5 | 1.2 ± 0.4 | 0.683 |
| Pro-BNP | 1281.1 ± 231.5 | 1469.5 ± 876.4 | 0.700 |
| Echo parameters | |||
| LVEF (%) | 59.1 ± 11.9 | 62.9 ± 13.5 | 0.006 |
| LVIDs (mm) | 31.2 ± 9.4 | 34.5 ± 7.9 | 0.001 |
| LVIDd (mm) | 46.8 ± 8.0 | 50.6 ± 6.6 | <0.001 |
| IVSD (mm) | 12.1 ± 3.7 | 10.8 ± 2.7 | <0.001 |
| LVPWD (mm) | 10.4 ± 2.2 | 9.9 ± 2.2 | 0.030 |
| LAVi (mL/m2) | 22.1 ± 17.9 | 24.8 ± 12.1 | 0.193 |
| E velocity (cm/s) | 0.7 ± 0.2 | 0.8 ± 0.3 | 0.266 |
| A velocity (cm/s) | 0.7 ± 0.2 | 0.7 ± 0.2 | 0.111 |
| E′ | 0.1 ± 0.03 | 0.1 ± 0.04 | 0.427 |
| E/E′ | 11.4 ± 6.6 | 11.9 ± 7.0 | 0.511 |
Values are mean ± SD (range). PVC indicates premature ventricular complex; DM, diabetes mellitus; HTN, hypertension; CAD, coronary artery disease; PCI, percutaneous coronary intervention, CABG, coronary artery bypass graft surgery; CCB, calcium channel blocker; ARB, angiotensin II receptor blocker; ACEi, angiotensin converting enzyme inhibitor; VKA, vitamin K antagonist; WBC indicates white blood cell count; fT4, free thyroxine 4; proBNP, pro-B type N-terminal peptide; LVEF, left ventricular ejection fraction; LVIDs, left ventricular systolic diameter; LVIDd, left ventricular diastolic diameter; IVSd, interventricular septal diameter; LAVi, left atrial volume index; E, the peak mitral flow velocity of the early rapid filling wave; A, peak velocity of the late filling wave due to atrial contraction; E′, early diastolic mitral annulus velocity; A′, late diastolic mitral annulus velocity.