Table 4.

Univariate and multivariate Cox analyses for PVCs-related stroke-like symptoms (A) and new-onset LV dysfunction (B) in patients with frequent idiopathic premature ventricular complex >10% at 4-year follow-up.

(A)	Univariate analysis		Multivariate analysis
Variable N (%)	OR (95% CI)	P-value	OR (95% CI)	P-value
Female (gender)	1.750 (1.001–3.174)	0.049
Non-sustained VT	2.265 (1.099–4.670)	0.027	2.501 (1.141–5.485)	0.022
Sinus QRS duration (ms)	0.985 (0.970–0.999)	0.050
PVC CI (ms)	0.036 (0.002–0.834)	0.038
Post- PVC CI (ms)	0.382 (0.148–0.987)	0.047
After V3 transition of Precordial R-wave	1.937 (1.032–3.638)	0.040	1.992 (1.017–3.914)	0.044
OR indicates odds ratio; CI, confidence interval; VT, ventricular tachycardia; PVC CI, PVC coupling interval - from the onset of the R wave of the previous sinus beat to the onset of the PVC; Post- PVC CI, from the onset of the PVC to initiation of the next sinus beat.

(B)	Univariate analysis		Multivariate analysis
Variable N (%)	OR (95% CI)	P-value	OR (95% CI)	P-value
Age	0.963 (0.924–0.994)	0.045
Before V3 transition of precordial R-wave	3.900 (1.136–13.387)	0.031
CI ratio	0.927 (0.871–0.987)	0.018	0.902 (0.815–0.999)	0.037
LAD	0.906 (0.834–0.986)	0.022
LVEF	1.083 (1.022–1.146)	0.006	1.326 (0.999–1.760)	0.049
LVEDV	0.980 (0.962–0.998)	0.030
LVESV	0.967 (0.941–0.994)	0.016

OR indicates odds ratio; CI, confidence interval; VT, ventricular tachycardia; PVC CI, PVC coupling interval - from the onset of the R wave of the previous sinus beat to the onset of the PVC; Post- PVC CI, from the onset of the PVC to initiation of the next sinus beat.

OR indicates odds ratio; CI, confidence interval; CI, coupling interval; LAD, left atrial diameter; LVEF, left ventricular ejection fraction; LVEDV, left ventricular end diastolic volume, LVESV, left ventricular end systolic volume.