FIG. 2.

White matter lesion identification on in vivo 3 Tesla magnetic resonance imaging (MRI) and ex vivo 7 Tesla MRI. An in vivo 3 Tesla MRI performed at age 88, after the patient's fifth TBI, revealed bihemispheric corona radiata and internal capsule white matter hyperintensities, including a punctate lesion at the posterior aspect of the putamen (arrow). The same lesion was identified by ex vivo 7 Tesla MRI (arrow), which was performed on the formalin-fixed right hemisphere. A zoomed view of the lesion is shown in the right panel (arrow) to demonstrate the increased anatomic precision provided by ex vivo MRI (200 μm resolution) for delineating the borders of the lesion with respect to nearby anatomic structures. Cd, caudate; GP, globus pallidus; Ins, insula; Put, putamen.