Table 1.
Basic characteristics of the included studies.
| Reference | Sample size(I/C) | Age(I/C) | Duration of disease(I/C) | Diagnosis standard | Intervention group | Control group | Treatment duration | Outcome |
|---|---|---|---|---|---|---|---|---|
| Chen H, 2012 | 68/51 | 42-59 (50.20 ± 3.94) /43-58 (50.78 ± 4.08) |
1.76 ± 0.99 y /1.91 ± 1.25 y |
Age; CCMD-3; HAMD |
OCHM + antidepressant | antidepressant | 8w | ①②④ |
|
| ||||||||
| Chu YH, 2005 | 30/30 | 41-60 (47.86 ± 4.42) /41-60 (48.3 ± 4.06) | NS | Age; CCMD-3; HAMD |
OCHM + HT | HT | 6w | ①② |
|
| ||||||||
| Guo LH, 2016 | 43/43 | 40-55/42-55 | (1.8 ± 0.6) y/(1.6 ± 0.8) y | Age; CCMD-3; HAMD |
OCHM + antidepressant | antidepressant | 6w | ② |
|
| ||||||||
| Jiang LX, 2016 | 98/98 | 41-60 (51.18 ± 4.52)/46-54(48.85 ± 3.27) | (4.8 ± 1.7) y/(4.2 ± 1.0) y | Age; CCMD-3; HAMD |
OCHM + antidepressant | antidepressant | 8w | ①②③④ |
|
| ||||||||
| Li QY, 2009 | 34/34 | 41-56 (46.8 ± 4.1) | NS | Age; ICD-10; HAMD |
OCHM + pharmacotherapy | pharmacotherapy | 4w | ①②④ |
|
| ||||||||
| Liu F, 2014 | 50/50 | 44-56 (49.3 ± 2.4) /43-57 (48.4 ± 2.3) |
(2.3 ± 0.5) y/(2.1 ± 0.4)y | Age; ICD-10 |
OCHM + antidepressant | antidepressant | 8w | ①② |
|
| ||||||||
| Liu R, 2007 | 30/30 | (54.32 ± 3.29) /(54.0 ± 4.62) |
(11.32 ± 6.25) m/(12.12 ± 4.58)m | Age; CCMD-3; HAMD |
OCHM + antidepressant | antidepressant | 8w | ①②④ |
|
| ||||||||
| Ni JP, 2014 | 37/33 | (52 ± 4)/(52 ± 4) | (9 ± 5) m/ (9 ± 5) m |
Age; CCMD-3; HAMD |
OCHM + antidepressant | antidepressant | 4w | ②④ |
|
| ||||||||
| Qu LX, 2010 | 30/30 | 45-55(51.6 ± 3.2) /45-55(50.8 ± 2.8) |
(10.5±2.7)m /(11.1±5.2)m |
Age; CCMD-3; HAMD |
OCHM + HT + antidepressant | HT + antidepressant | 8w | ①②④ |
|
| ||||||||
| Shi LR, 2016 | 45/45 | 41-58(46.4 ± 4.2) /42-57(44.8 ± 3.3) |
(11.7 ± 4.5)m /(10.6 ± 6.3)m |
Age; CCMD-3; HAMD |
OCHM + HT + antidepressant | HT + antidepressant | 12w | ①② |
|
| ||||||||
| Sun GC, 2015 | 40/40 | 42.2 ± 2.60 /42.2 ± 2.60 |
(1.92 ± 1.06) y /NS | Age; ICD-10; HAMD |
OCHM + antidepressant | antidepressant | 4w | ① |
|
| ||||||||
| Sun YH, 2013 | 38/38 | 43-48(44.76 ± 2.24) /42-49(45.02 ± 3.15) |
(2.38 ± 1.24) y /(2.54 ± 1.56)y |
Age; CCMD-3; HAMD |
OCHM + HT + antidepressant | HT + antidepressant | 4w | ② |
|
| ||||||||
| Wang CG, 2015 | 46/46 | 44-53(46.93 ± 6.8) /44-53(47.52 ± 7.2) |
NS | Age; CCMD-3 |
OCHM + antidepressant | antidepressant | 6w | ①④ |
|
| ||||||||
| Wang SF, 2015 | 40/40 | 43-50(46.45 ± 6.15) /42-49(45.82 ± 5.45) |
(2.75 ± 0.35)y /(2.85 ± 0.43)y |
Age; CCMD-3; HAMD |
OCHM + HT + antidepressant | HT + antidepressant | 3w | ① |
|
| ||||||||
| Wang XL, 2011 | 60/60 | 45-55(51.21 ± 3.17) /45-55(50.86 ± 3.41) |
NS | Age; CCMD-3; HAMD |
OCHM + HT + antidepressant | HT + antidepressant | 8w | ① |
|
| ||||||||
| Wang Y, 2015 | 30/30 | 45.20 ± 2.90 /44.80 ± 3.10 |
NS | Age; ICD-10; HAMD |
OCHM + antidepressant | antidepressant | 8w | ①②③④ |
|
| ||||||||
| Zhang CH, 2013 | 40/40 | 43-56(46.80 ± 4.10) /44-55(45.40 ± 3.2) |
(11.50±4.30)m /(10.90±6.50)m |
Age; CCMD-3; HAMD |
OCHM + HT + antidepressant | HT + antidepressant | 3w | ①② |
|
| ||||||||
| Zhang CH, 2011 | 30/30 | 45-55(43.50 ± 12.43) /45-55(42.25 ±11.38) |
NS | Age; CCMD-3; HAMD |
OCHM + antidepressant | antidepressant | 6w | ①② |
|
| ||||||||
| Zhang GQ, 2009 | 38/34 | 45-56(51.63 ± 3.68) /45-56(51.95 ± 3.86) |
(9.44 ± 4.69)m /(8.88 ± 4.65) m |
Age; CCMD-3; HAMD |
OCHM + antidepressant | antidepressant | 4w | ①②④ |
|
| ||||||||
| Zhang HZ, 2014 | 20/20 | 45-53 /46-52 |
(6-24)m /(5-22)m |
Age; CCMD-3 |
OCHM + HT | HT | 12w | ①②③ |
|
| ||||||||
| Zhang SJ, 2012 | 27/27 | 43-54(46.5 ± 6.3) /44-55(45.3 ± 7.2) |
(3.2 ± 2.8)m /(4.1 ± 3.2)m |
Age; DSM-IV |
OCHM + antidepressant | antidepressant | 4w | ② |
|
| ||||||||
| Zhang XH, 2014 | 27/27 | (47 ± 6.8) /(46.0 ± 6.8) |
NS | Age; CCMD-3; HAMD |
OCHM + antidepressant | antidepressant | 8w | ①② |
CCMD-3: Criteria for Classification and Diagnosis of Mental Diseases; DSM-IV: Diagnostic and Statistical Manual; ICD-10: International Classification of Disease; m = month; y = year; NS: not stated.OCHM: oral Chinese herbal medicine; HT: hormone therapy; w = week; ①: Hamilton Rating Scale for Depression (HAMD) score; ②: response rate; ③: Kupperman Menopausal Index (KMI) score; ④: adverse events (AEs).