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T2-high and T2-low asthma pathway. The T2-high subtype is characterized by the presences of high level of eosinophils in airways, and the T2-low subtype is characterized by Neutrophilic or Paucigranulocytic airway inflammation. APC antigen presenting cell, ILC2 type 2 innate lymphoid cells, TSLP thymic stromal lymphopoietin, and TNF (tumor necrosis factor).
