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. 2018 Jun 11;2018:2682037. doi: 10.1155/2018/2682037

Figure 2.

Figure 2

Effects of antipsychotic drugs on acetylated histone H3 and methyl CpG-binding protein 2 (MeCP2) levels at BDNF promoter IV in the rat hippocampus. Rats were given a daily injection of either VEH, OLA, or HAL for 21 d in conjunction with either + stress or − stress. Chromatin immunoprecipitation (ChIP) assays were performed to measure the levels of acetylated H3 (a) and MeCP2 (b) at BDNF promoter IV in the rat hippocampus using specific antibodies. These levels were quantified by a qRT-PCR procedure. ∗∗ p < 0.01 versus vehicle control; †† p < 0.01 versus vehicle + stress.