TABLE 2 .

Summary of β-barrel allele profiles and molecular types in clinical samples with complete OMP profiles and belonging to either the Nichols or SS14 clade

Clade	No. of samples	tprC β-barrel(s)	tprD/D2 β-barrel	bamA β-barrel	Reference genome OMP profilea	ECDCTb
Nichols	1	Nichols	D	Nichols	Nichols	XX/a (1)
	2	Mexico A/PT_SIF	D2	Mexico A	Mexico A	14d/d (1), 21a/d (1)
	2	Sea81-4	D2	Sea81-4	Sea81-4	14d/d (1), 14X/d (1)
SS14	10	Mexico A/PT_SIF	D2	Mexico A	Mexico A	12d/f (1), 14d/f (5), 14b/f (1), 14d/g (2), 15a/e (1)
	8	Mexico A/PT_SIF	D2	SS14	Amoy	XX/f (1), 14d/k (1), 14d/g (5), 14e/g (1)
	2	Mexico A/PT_SIF	D2	Nichols	Unique	14d/X (1), XX/f (1)

^aData are based on matching the reference genome at all three OMP loci.

^bNumbers in parentheses indicate numbers of clinical samples containing T. pallidum subsp. pallidum of the corresponding ECDC type. X, undetermined genotype.