TABLE 4 .

Antibiotic IC₅₀s of the WT and Rv0078 strains

Drug	IC50 for:
	Parental strain	ΔRv0078::hyg mutant
Ethionamide	1.0–2.3 µg/ml	0.8–1.3 µg/ml
Ciprofloxacin	0.1–0.2 µg/ml	0.1–0.2 µg/ml
Ethambutol	0.6–2 µg/ml	0.6–2 µg/ml
Isoniazid	32–44 ng/ml	29–44 ng/ml
Meropenema	1 µg/ml	1 µg/ml
Norfloxacin	2 µg/ml	2 µg/ml
Rifampin	32–38 ng/ml	32–38 ng/ml
Streptomycin	0.3–0.6 µg/ml	0.3–0.4 µg/ml
Vancomycina	3–10 µg/ml	6–10 µg/ml

^aSupplemented with 5 µg/ml potassium clavalunate. See Materials and Methods for details.