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. 2018 Jun 19;13:3507–3527. doi: 10.2147/IJN.S166445

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© 2018 Chen et al. This work is published and licensed by Dove Medical Press Limited

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In vivo fluorescence imaging of PPP_Cy5-RH-NPs in the DN and healthy C57BL/6 mice.

Notes: The mice were i.v. treated with PPP_Cy5-RH-NPs and observed from 1 to 6 h by IVIS Lumina III; at the end of in vivo fluorescence imaging, the organs were dissected and measured (A). Fluorescent quantitative analysis by total fluorescence intensity per organ (B). ^**P < 0.01 vs HC group.

Abbreviations: Cy5, cyanine 5; DN, diabetic nephropathy; DNC, DN control; HC, healthy control; i.v., intravenously; Max, maximum; Min, minimum; RH, rhein; RH-sol, RH solution.