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16-week-old C57BL/6J female mice immobilized with botulinum toxin (BTX) and treated with zoledronic acid (Zol) compared with baseline (Base) and control (Ctrl) mice. Fracture strength and maximum stiffness acquired by mechanically testing the femoral mid-diaphysis and neck. a denotes a significant difference (p<0.05) from Base, b denotes a significant difference (p<0.05) from Ctrl, and c denotes a significant difference (p<0.05) from BTX. Mean ± SD.
