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Proportion of patients with Grades 1–5 toxicities attributed to ch14.18 on COG study ANBL0931.
| Pain (%) | Allergic reactions (%) | Capillary leak syndrome (%) | Hypotension (%) | Fever (%) | Ocular toxicity (%) | |
|---|---|---|---|---|---|---|
| Course 1 (n = 104) | 93 | 25 | 24 | 60 | 91 | 2 |
| Course 2 (n = 100) | 78 | 28 | 39 | 64 | 92 | 3 |
| Course 3 (n = 98) | 79 | 16 | 14 | 58 | 69 | 3 |
| Course 4 (n = 90) | 77 | 21 | 33 | 69 | 87 | 1 |
| Course 5 (n = 88) | 70 | 13 | 17 | 52 | 67 | 1 |
| Course 6 (n = 81) | 26 | 0 | 0 | 14 | 19 | 0 |
