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. 2018 Jul;198:247–253.e1. doi: 10.1016/j.jpeds.2018.03.030

Table III.

Step-wise backwards multivariable linear and logistic regression modeling to assess the relationship between eGFR, ON-Marg summary score, and other variables of interest

Variables Linear regression Zappitelli eGFR (mL/min/1.73 m2)
Logistic regression NF vs HF
β SE P Adj R2 β SE P Adj R2
Intercept 114.3 13.6 <.0001 −3.09 1.88 .1001
Age at baseline −2.4 0.7 .00083 0.04 −0.20 0.10 .047 0.016
Sex [female] 11.0 2.4 <.0001 0.074 0.90 0.39 .0082 0.03
BMI z score −4.0 1.4 .0034 0.03
Ethnicity [nonwhite] 7.3 2.5 .0033 0.03 0.67 0.34 .047 0.015
Glucose, mmol/L 0.8 0.3 .0027 0.03 0.09 0.04 .025 0.02
HbA1c, % 1.3 1.0 .174 0.003 0.25 0.13 .062 0.014
ON-Marg 6.1 1.6 .00029 0.04 0.54 0.22 .017 0.022
Adjusted R2 0.278 0.1406

Continuous eGFRZappitelli was used for the linear model whereas the logistic model compared subjects with normofiltration (n = 127; eGFRZappitelli < 126.8 mL/min/1.73 m2) with those with hyperfiltration (n = 72; eGFRZappitelli ≥ 126.8 mL/min/1.73 m2).