Table 1.
Correlation of miR-145 expression with the clinicopathological features of patients with LSCC
| Parameters | Patients n (%) | miR-145 level | P-value |
|---|---|---|---|
| Total | 132 | ||
| Sex | 0.408 | ||
| Male | 114 (86.4) | 4.14±2.98 | |
| Female | 18 (13.6) | 3.54±1.58 | |
| Age (years) | 0.343 | ||
| ≥60 | 84 (63.6) | 3.88±2.07 | |
| <60 | 48 (36.4) | 4.36±3.82 | |
| Primary site | 0.671 | ||
| Glottic | 76 (57.6) | 3.96±2.42 | |
| Supraglottic | 56 (42.4) | 4.18±3.32 | |
| T stage | 0.021 | ||
| T2 | 51 (38.6) | 5.13±3.80 | |
| T3 T4 | 81 (61.4) | 3.38±1.69 | |
| Differentiation | 0.013 | ||
| High | 85 (64.4) | 4.68±3.19 | |
| Moderate and low | 47 (35.6) | 2.93±1.47 | |
| Neck lymph node metastasis | 0.005 | ||
| N+ | 61 (46.2) | 2.85±1.41 | |
| N− | 71 (53.8) | 5.09±3.31 | |
| Perinodal invasion | 0.588 | ||
| + | 21 (45.7) | 3.87±2.53 | |
| − | 25 (54.3) | 4.30±2.97 | |
| Lymphovascular and perineural invasion | 0.495 | ||
| + | 13 (28.3) | 3.73±3.01 | |
| − | 33 (71.7) | 4.28±2.85 |
Note: The data is presented as mean ± SD.
Abbreviations: LSCC, laryngeal squamous cell carcinoma; miR-145, microRNA-145.