Table 1.

Characteristics of Existing IT Infrastructures at the U-PGx Implementation Sites

Infrastructure characteristics	NL	GB	IT	ES	AT	SI	GR
EHR inpatient setting	Yes	Yes	Partially	Yes	Partially	Partially	No
EHR outpatient setting	Yes	Partially	Partially	Yes	No	No	No
Text reports	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Active CDS	Yes (for PGx, DDIs, contraindications, and drug dose)	Yes (for allergies and DDI)	No	Yes (for allergies)	No	No	No
Passive CDS	No	Yes	Yes	Yes	Yes	No	No
LIMS	Yes	Yes	Yes	Yes	Yes	Yes	No
Structured laboratory results	Yes	Yes	Yes	Yes	Yes	No	No

Abbreviations: AT, Austria; DDI, Drug-drug interactions; EHR, Electronic health record; ES, Spain; GB, Great Britain; GR, Greece; IT, Italy; LIMS, Laboratory information management system; NL, The Netherlands; PGx, Pharmacogenomics; SI, Slovenia.

Participating healthcare institutions as of August 2017: NL: A network of primary care physicians and pharmacies established by the department of Clinical Pharmacy & Toxicology of the Leiden University Medical Center (LUMC); Department of Neurology, LUMC; Outpatient Pharmacy, LUMC. GB: The Royal Liverpool University Hospital. IT: Medical Oncology and Radiotherapy Oncology Unit of the National Cancer Institute in Aviano and Treviso, Medical Oncology and Radiotherapy Oncology Unit of the San Filippo Neri Hospital in Rome. ES: Departments of Pharmacy and Cardiology of the San Cecilio University Hospital in Granada. AT: Department of Nephrology and Dialysis of the Vienna General Hospital. SI: Kidney transplant center, Nephrology Clinic, University Clinical Center Ljubljana; Health Care Center Ljubljana, Health Care Center Kocevje, Health Care Center Litija; University Psychiatry Clinic Ljubljana.GR: Department of Pharmacy, University of Patras; Psychiatric Clinic, Cardiology Clinic and Oncology Clinic of the General University Hospital in Patras.