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. 2018 Apr 10;24(4):416–441. doi: 10.1093/humupd/dmy009

Table II.

Presence of immune cells in the normal testis and epididymis of adult mouse and human.

Immune cells Common markers Testis Epididymis
Mousea Human Mouse Human
  • Macrophages

  •  M1 classically activated

  •  M2 alternatively activated

  • CD68, F4/80 (mouse), CD11b

  • CD86, MHC class II

  • CD163, CD206

+++ +++ + +
Dendritic cells CD11c, CD209, MHC class II, CD80, CD86 + (+) ++b ++
T cells CD3, CD4, CD8, Foxp3 + + + +
B cells CD19, CD 20, B220 (CD45R) + (+) +/− ?
Natural killer cells CD56, CD161 (NK1.1) + (+) ? ?
Mast cells
  • Tryptase

  • Fc epsilon RI alpha, CD117 (c-kit), CD23, CD203c

(+) + + +

aConcerning the overall occurrence of immune cell subpopulations, comparable results exist for the rat; btubular wall.

(+) Very few.

+++ Abundant.

MHC, major histocompatibility complex.