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. 2018 Apr 14;164(1):339–352. doi: 10.1093/toxsci/kfy090

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© The Author(s) 2018. Published by Oxford University Press on behalf of the Society of Toxicology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contactjournals.permissions@oup.com

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Figure 2. — The cytotoxicity of OH-GQDs and their effects on cell cycle distribution. (A and B) Cell viability after exposure to indicated concentration of OH-GQDs (0, 25, 50, 100, and 200 μg/ml) for 24 and 48 h, respectively. One-way ANOVA was performed and data are presented as mean ± SD, n = 5. When compared with 0 μg/ml OH-GQDs-treated cells, *p < .05, **p < .01, ***p < .001. (C and D) HET-1A cells were exposed to 25 and 50 μg/ml OH-GQDs for 24 or 48 h and cell cycle distribution was analyzed by flow cytometry. One-way ANOVA was performed. The data are presented as the mean ± SD from 3 tests. When compared with the control cells which were harvested at the same time point, *** p < .001.