Table 2.
Top 20 Genes Upregulated Within OH-GQDs- and Vehicle-Treated HET-1A Cells (OH-GQDs-Treated versus Vehicle-Treated Cells)
| Gene Name | Fold Change Upregulated | P-Value | Chromosome | Definition |
|---|---|---|---|---|
| SLC6A13 | 56.18 | 5.29E-05 | chr12 | Solute carrier family 6 (neurotransmitter transporter), member 13 |
| ATF3 | 35.58 | 9.44E-07 | chr1 | Activating transcription factor 3 |
| HMOX1 | 30.29 | 1.32E-06 | chr22 | Heme oxygenase (decycling) 1 |
| RSAD2 | 30.06 | 2.75E-05 | chr2 | Radical S-adenosyl methionine domain containing 2 |
| IL10RA | 26.34 | 8.14E-06 | chr11 | Interleukin 10 receptor, alpha |
| FRZB | 26.18 | 2.18E-05 | chr2 | Frizzled-related protein |
| PLCB1 | 24.94 | 9.95E-06 | chr20 | Phospholipase C, beta 1 (phosphoinositide-specific) |
| AOC3 | 24.72 | 9.85E-04 | chr17 | Amine oxidase, copper containing 3 |
| EGR4 | 24.38 | 3.61E-06 | chr2 | Early growth response 4 |
| MAFB | 23.92 | 5.57E-07 | chr20 | V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| COL20A1 | 23.7 | 7.12E-04 | chr20 | Collagen, type XX, alpha 1 |
| JUN | 23.39 | 1.30E-06 | chr1 | Jun proto-oncogene |
| LIPN | 22.56 | 2.10E-02 | chr10 | Lipase, family member N |
| PYGM | 21.37 | 8.08E-05 | chr11 | Phosphorylase, glycogen, muscle |
| CTGF | 21.29 | 8.22E-07 | chr6 | Connective tissue growth factor |
| GADD45G | 20.76 | 6.35E-09 | chr9 | Growth arrest and DNA-damage-inducible, gamma |
| CDRT1 | 20.46 | 1.91E-05 | chr17 | CMT1A duplicated region transcript 1 |
| OASL | 18.04 | 2.64E-06 | chr12 | 2′-5′-oligoadenylate synthetase-like |
| ANKRD1 | 17.65 | 5.55E-06 | chr10 | Ankyrin repeat domain 1 (cardiac muscle) |
| FAM71F1 | 16.84 | 4.91E-06 | chr7 | Family with sequence similarity 71, member F1 |