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. 2018 Apr 4;164(1):264–277. doi: 10.1093/toxsci/kfy081

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© The Author(s) 2018. Published by Oxford University Press on behalf of the Society of Toxicology.

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Figure 5. — Distribution of immunoreactive cells for (A) FBJ osteosarcoma oncogene (FOS), (B) activity-regulated cytoskeleton-associated protein (ARC), and (C) cyclooxygenase-2 (COX-2) in the GCL of the hippocampal dentate gyrus of male offspring at PND 21 and PND 77 after maternal exposure to aluminum chloride (AlCL₃) from GD 6 to PND 21. Representative images from the 0-ppm controls (left) and the 900-ppm (middle) and 1800-ppm (right) AlCL₃ groups at PND 21. Magnification ×400; bar 50 μm. Graphs show the numbers of immunoreactive cells in the GCL. N = 9–12/group (PND 21: 0-ppm controls, 10; 900-ppm AlCL₃, 10; 1800-ppm AlCL₃, 10; PND 77: 0-ppm controls, 12; 900-ppm AlCL₃, 9; 1800-ppm AlCL₃, 11). **p < .01, compared with the 0-ppm controls by Dunnett’s test or Aspin-Welch’s t-test with Bonferroni correction.