Skip to main content
. 2018 Apr 4;164(1):264–277. doi: 10.1093/toxsci/kfy081

Table 1.

Body and Brain Weights of Offspring on PND 21 and PND 77

AlCl3 in Drinking Water (ppm)
0 (Control) 900 1800
PND 21
 Males
  No. of offspring examined 36 30 33
   Body weight (g) 17.9 ± 0.9 16.9 ± 1.3 15.6 ± 0.8**
  No. of offspring examined 24 20 22
   Brain weight (g) 0.45 ± 0.02 0.44 ± 0.01 0.43 ± 0.01
         (g/100g body weight) 2.50 ± 0.15 2.65 ± 0.26 2.79 ± 0.18**
 Females
  No. of offspring examined 24 20 22
   Body weight (g) 17.4 ± 0.7 15.7 ± 1.5** 15.1 ± 0.7**
   Brain weight (g) 0.44 ± 0.01 0.43 ± 0.01 0.43 ± 0.02*
         (g/100g body weight) 2.58 ± 0.19 2.82 ± 0.24* 2.90 ± 0.13**
PND 77
 Males
  No. of offspring examined 32 23 39
   Body weight (g) 53.0 ± 2.8 53.0 ± 4.7 48.3 ± 2.1**
  No. of offspring examined 20 13 28
   Brain weight (g) 0.50 ± 0.01 0.50 ± 0.02 0.50 ± 0.02
         (g/100g body weight) 0.98 ± 0.08 0.94 ± 0.10 1.04 ± 0.08
 Females
  No. of offspring examined 28 27 16
   Body weight (g) 42.5 ± 4.4 43.7 ± 2.7 40.5 ± 3.4
   Brain weight (g) 0.51 ± 0.02 0.49 ± 0.02 0.48 ± 0.03*
         (g/100g body weight) 1.85 ± 0.08 1.89 ± 0.09 1.95 ± 0.17

Abbreviations: PND, postnatal day; AlCl3, aluminum chloride.

Data are expressed as the mean ± SD.

*

p < .05,

**

p < .01, compared with the 0-ppm controls by Dunnett’s test or Aspin-Welch’s t-test with Bonferroni correction.