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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Biochim Biophys Acta. 2018 Mar 15;1861(5):497–508. doi: 10.1016/j.bbagrm.2018.03.001

Figure 1. Increased expression of viral miRNAs in diseased periodontal tissues.

Figure 1

Expression analysis of candidate viral miRNAs in healthy and diseased gingival samples. Total RNA was isolated from healthy and diseased tissues (n=6 subjects/group). Expression of three viral miRNAs (A) miR-H1, (B) miR-K12-3-3p and (C) miR-US4 were detected by quantitative RT-PCR. (D) Quantification of HSV-1 encoded ICP0 transcript was assessed by RT-PCR in healthy and diseased gingival biopsies. Numbers of positive samples are mentioned for each group. Student’s t-test was used to calculate p-values. **p<0.01; ***p<0.001.