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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Biochim Biophys Acta. 2018 Mar 15;1861(5):497–508. doi: 10.1016/j.bbagrm.2018.03.001

Figure 2. Differential expression of host genes in miR-H1 and miR-K12-3-3p transfected HOK.

Figure 2

Viral miRNA transfected HOK cells were assessed for whole transcriptome using microarray analysis. The number of upregulated and downregulated genes in (A) miR-H1 and (B) miR-K12-3-3p transfected cells (n=4). (C) Venn diagram showing list of unique and commonly expressed genes in miR-H1 and miR-K12-3-3p overexpressing HOK. (D) Validation of selected differentially expressed genes by quantitative RT-PCR in a second cohort of HOK cultures. Total RNA isolated from miR-H1, miR-K12-3-3p and control transfected HOK were analyzed for the expression of differentially expressed genes by quantitative RT-PCR. Data is presented as ±SEM of four independent experiments. Student’s t-test was conducted to calculate p-values. *p<0.05, **p < 0.01