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. 2018 Jun 13;12(6):e0006565. doi: 10.1371/journal.pntd.0006565

Table 1. Percentage yields and IC50s of the extracts in secondary screens for the male, female and microfilariae (mf) of Onchocerca ochengi and the mf of Loa loa.

Plant part/ solvent for extraction Extract code Extraction Yield IC50 (μg/mL) for % inhibition of O. ochengi male worm motility IC50 (μg/mL) for % inhibition of formazan formation by O. ochengi female worm IC50 (μg/mL) for % inhibition of O. ochengi mf motility IC50 (μg/mL) for % inhibition of L. loa mf motility
Tamarindus indica leaves/ hexane TILhex 3.0 18.3 294.2 62.5 7.8
Tamarindus indica leaves/ methylene chloride TILmc 3.6 250 62.5 31.3 64.5
Tamarindus indica roots/ hexane TIRhex 2.7 37.9 70.2 62.5 64.5
Tamarindus indica roots/ methanol TIRmet 6.5 45.4 121.2 385.2 250
Tamarindus indica stem bark/ hexane TIBhex 1.5 112.4 178.8 62.5 88.4
Tamarindus indica stem bark/ methylene chloride TIBmc 2.2 112.4 102.8 62.5 93.4
Lantana camara leaves/ hexane LCLhex 1.2 7.3 35.1 3.8 62.5
Lantana camara leaves/ methylene chloride LCLmc 3.3 7.8 125 3.9 55.6
Lantana camara leaves/ methanol LCLmet 1.1 33.2 111.2 7.3 93.4
Lantana camara stem bark/ methylene chloride LCBmc 3.5 9.5 176.8 56.1 125
Lantana camara stem bark/ methanol LCBmet 5 80.11 222.5 177.6 95.1
Lantana camara root / hexane LCRhex 3 58.8 222.5 257.9 257.9