Figure 3.

The rate of reaction of KAD synthesis in organic solvents with various dipole moments (D) where the reaction time, temperature, substrate molar ratio, agitation and enzyme loading were fixed at 12 h, 50 °C, 5:1, 180 rpm and 1.25% (v/v), respectively. Letters a, b, and c indicate significant difference at p <0.05 with Bonferroni’s multiple comparison test. Note: HEX: Hexane; TOL: Toluene; CHL: Chloroform; THF: Tetrahydrofuran; EtOAc: Ethyl acetate; ACE: Acetone; MeCN: Acetonitrile; DMSO: Dimethyl sulfoxide.