Figure 2.

Competitive binding of the complex of heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) and G-quadruplex with various oligonucleotides: natural telomere RNA (Native-RNA-Gq) (a); DNA loop (DNA-loop-Gq) (b); 2′-O-methyl ribonucleotide (2′-O-Me-loop-Gq) (c); the abasic RNA loop (R-abasic-loop-Gq) (d); and the abasic DNA loop (D-abasic-loop-Gq) (e). Ratios indicated on the upper. RNA-protein complexes were resolved by 8% polyacrylamide gel electrophoresis and visualized by autoradiography.