Table III.
mRNA expression of TRIM27 in colorectal carcinoma and adjacent normal tissues.
| Clinical feature | n (%) |
TRIM27 expression
|
P-value | |
|---|---|---|---|---|
| High, n (%) | Low, n (%) | |||
| Sex | 40 | 40 | ||
| Male | 52 (65.0) | 25 (31.3) | 27 (33.8) | 0.639 |
| Female | 28 (35.0) | 15 (18.7) | 13 (16.2) | |
| Age (years) | ||||
| >60 | 36 (45.0) | 17 (21.3) | 19 (23.8) | 0.653 |
| ≤60 | 44 (55.0) | 23 (28.7) | 21 (26.2) | |
| Depth of invasion | ||||
| T1/T2 | 21 (26.3) | 5 (6.3) | 16 (20.0) | 0.005b |
| T3/T4 | 59 (73.7) | 35 (43.7) | 24 (30.0) | |
| Lymph node metastasis | ||||
| Absent | 39 (48.8) | 14 (17.5) | 25 (31.3) | 0.014a |
| Present | 41 (51.2) | 26 (32.5) | 15 (18.7) | |
| Tumor stage | ||||
| I/II | 37 (46.3) | 12 (15.0) | 25 (31.2) | 0.004b |
| III/IV | 43 (53.7) | 28 (35.0) | 15 (18.8) | |
| Liver metastasis | ||||
| Yes | 10 (12.5) | 8 (10.0) | 2 (2.5) | 0.043a |
| No | 70 (87.5) | 32 (40.0) | 38 (47.5) | |
| Location | ||||
| Rectum | 35 (43.8) | 19 (23.8) | 16 (20.0) | 0.499 |
| Colon | 45 (56.2) | 21 (26.2) | 24 (30.0) | |
| CEA (ng/ml) | ||||
| <4.7 | 31 (38.8) | 13 (16.2) | 18 (22.5) | 0.250 |
| >4.7 | 49 (61.2) | 27 (33.8) | 22 (27.5) | |
a
P<0.05;
b
P<0.01. TRIM27, tripartite motif-containing 27.