Table I.
Association between NRG1 and lymph node metastasis in patients with thyroid cancer according to immunohistochemical analysis and patient outcomes.
| Tumor tissue | Regional lymph node metastasisa
|
Recurrence (local or distant)b
|
||
|---|---|---|---|---|
| Negative | Positive | Negative | Positive | |
| NRG1 | ||||
| − | 43 (22.0) | 24 (12.2) | 66 (33.7) | 1 (0.5) |
| + | 21 (10.7) | 36 (18.4) | 49 (25) | 8 (4.1) |
| ++ | 23 (11.7) | 49 (25.0) | 60 (30.6) | 12 (6.1) |
Data are presented as number (n) and the percentage in parentheses.
a
Pearson’s χ2 test=16.462, P=0.001;
b
Pearson’s χ2 test=9.280, P=0.010. NRG1, neuregulin 1.