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. 2018 May 11;53(2):603–619. doi: 10.3892/ijo.2018.4404

Table III.

Associations between the expression levels of the differentially expressed autophagy-related genes and the clinicopathological characteristics of the patients with thyroid cancer.

Genes Age (≥60/<60)
Sex (male/female)
Tumor status (with tumor/ tumor free)
Primary neoplasm focus type (multifocal/unifocal)
Pathological stage (III–IV/I–II)
T stage (T3-T4/T1-T2)
N stage (N1–3/N0)
M stage (M1/M0)
t P t P t P t P t P t P t P t P
PRKCQ 0.738 0.461 1.769 0.077 −0.586 0.561 2.177 0.030 −4.205 <0.001 −4.422 <0.001 −7.517 <0.001 −0.925 0.356
BID −2.118 0.036 0.116 0.908 −0.863 0.388 0.249 0.803 2.455 0.015 2.939 0.003 7.215 <0.001 0.015 0.988
DNAJB1 −0.404 0.686 −2.022 0.044 0.611 0.544 −1.113 0.266 1.602 0.110 1.623 0.105 0.722 0.471 −0.780 0.436
SERPINA1 −1.395 0.165 −0.159 0.874 −0.955 0.340 −0.254 0.800 4.473 <0.001 4.128 <0.001 8.000 <0.001 −0.269 0.788
JUN −0.803 0.422 −1.160 0.247 0.817 0.414 −1.061 0.289 −1.977 0.049 −1.201 0.230 −0.869 0.385 −0.368 0.713
BCL2 −0.429 0.668 −0.140 0.888 −0.851 0.395 1.360 0.174 −5.356 <0.001 −5.008 <0.001 −7.931 <0.001 −0.180 0.857
ITGA3 −1.303 0.194 −0.474 0.635 0.064 0.949 −0.939 0.348 4.597 <0.001 4.925 <0.001 8.375 <0.001 0.700 0.484
CX3CL1 −1.720 0.086 −0.327 0.744 −1.417 0.157 −0.636 0.525 1.142 0.254 1.311 0.190 3.531 <0.001 −0.369 0.712
ITPR1 0.422 0.673 0.602 0.548 0.959 0.338 1.070 0.285 −4.242 <0.001 −4.572 <0.001 −5.818 <0.001 0.484 0.628
BCL2L1 −1.200 0.231 1.396 0.163 −0.406 0.685 −0.594 0.553 3.915 <0.001 4.228 <0.001 6.575 <0.001 −1.061 0.289
BAX −0.846 0.398 1.439 0.151 −0.642 0.521 −2.220 0.027 2.903 0.004 2.424 0.016 1.684 0.093 −0.017 0.986
EVA1A −1.193 0.233 −0.652 0.514 −0.175 0.861 −0.946 0.344 3.751 <0.001 3.992 <0.001 7.606 <0.001 0.174 0.862
TP53INP2 0.273 0.785 0.386 0.700 0.264 0.792 1.582 0.114 −5.373 <0.001 −4.559 <0.001 −6.27 <0.001 −0.246 0.806
CDKN2A 1.427 0.155 −0.257 0.797 1.009 0.318 −3.076 0.002 3.555 <0.001 4.166 <0.001 4.892 <0.001 0.429 0.668
PPP1R15A −1.923 0.055 −0.887 0.375 1.112 0.267 −1.050 0.294 −0.448 0.654 −0.078 0.938 1.984 0.048 0.067 0.947
DRAM1 −2.823 0.005 0.104 0.918 −1.486 0.138 0.696 0.487 1.918 0.056 1.813 0.070 6.336 <0.001 −0.561 0.575
DIRAS3 −1.781 0.077 −0.414 0.679 −0.326 0.744 0.408 0.684 1.648 0.100 0.637 0.525 2.936 0.004 0.811 0.418
ITGB4 −0.674 0.500 0.638 0.524 −0.068 0.946 −0.773 0.440 3.519 <0.001 3.228 0.001 6.604 <0.001 −0.038 0.970
FOS 0.275 0.783 −1.45 0.148 0.320 0.749 0.147 0.883 −2.484 0.013 −1.871 0.062 −1.584 0.114 −0.078 0.938
DAPK2 −2.154 0.032 0.963 0.336 −0.939 0.348 −0.513 0.608 3.144 0.002 3.324 0.001 5.245 <0.001 0.054 0.957
SPHK1 −0.124 0.901 −0.415 0.678 −0.210 0.834 −1.400 0.162 5.177 <0.001 4.727 <0.001 5.811 <0.001 0.628 0.530
CTSB 0.843 0.399 −1.909 0.057 −1.768 0.078 −0.474 0.636 2.563 0.011 2.866 0.004 1.413 0.158 −0.257 0.798
IL24 0.535 0.593 0.686 0.493 −0.357 0.721 −1.435 0.152 2.83 0.005 1.724 0.085 5.371 <0.001 −0.944 0.346
CDKN1A −1.840 0.066 −0.475 0.635 −1.183 0.243 −2.734 0.006 0.379 0.705 1.311 0.190 1.898 0.058 −0.329 0.742
TP63 −2.005 0.046 −0.174 0.862 0.152 0.879 1.096 0.274 1.017 0.31 0.358 0.721 6.862 <0.001 −0.185 0.858
MAP1LC3C 0.536 0.592 −1.159 0.247 0.122 0.903 −0.760 0.448 −1.689 0.092 −2.294 0.022 −3.439 0.001 −0.989 0.323
CCL2 0.289 0.772 −0.22 0.826 −1.154 0.249 −1.192 0.234 1.635 0.103 1.194 0.233 3.221 0.001 −1.761 0.079
CXCR4 −1.925 0.055 −0.543 0.587 −0.075 0.940 0.239 0.811 −0.311 0.756 0.739 0.460 3.417 0.001 −0.325 0.746
HSPB8 −1.178 0.240 −1.060 0.290 −0.581 0.561 −0.999 0.318 −2.801 0.005 −1.221 0.223 −2.123 0.034 −1.446 0.149
ATG9B −0.027 0.979 0.908 0.364 0.761 0.447 −1.963 0.050 2.011 0.045 1.896 0.059 1.977 0.049 0.647 0.536
GRID2 0.846 0.980 0.436 0.663 1.504 0.133 −1.342 0.180 −0.049 0.961 0.403 0.687 −2.785 0.006 1.779 0.076