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[11C]8 PET images in a first-in-human study. (A) Brain SUV images averaged from 60 to 90 min p.i. of [11C]8 (174 MBq). PET images are overlaid on MRI; (B) [11C]8 SUVR images of eight individual subjects. SUV60–90 min was normalized to white matter as a reference. (Reproduced with permission from Wey et al. Sci Transl Med; The American Association for the Advancement of Science, 2016 [28]).
