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. 2018 Jan 20;23(1):223. doi: 10.3390/molecules23010223

Table 1.

IC50 values of baicalein and Trolox in various assays.

Assays Baicalein
μM
Trolox
μM
Ratio value
IC50, Trolox/IC50, Baicalein
•OH-scavenging 93.7 ± 1.6 a 137.6 ± 3.6 b 1.46
PTIO• scavenging * 188.7 ± 13.1 a 384.2 ± 23.3 b 2.03
Cu2+ reducing 19.0 ± 0.1 a 44.6 ± 1.5 b 2.34
FRAP 11.1 ± 0.0 a 12.0 ± 0.0 a 0.96

IC50 value was defined as the final concentration of 50% radical-scavenging (relative reducing power), was calculated by linear regression analysis, and is expressed as the mean ± SD (n = 3). Linear regression was analyzed using Origin 6.0 professional software. The mean values with different superscripts (a or b) in the same row, are significantly different (p < 0.05). * The assay was conducted at pH 7.4. The ratio value is defined as IC50, Trolox/IC50, Baicalein. FRAP, Fe3+ reducing antioxidant power assay. PTIO•, 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide radical.