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Scutellarin decreases microgliosis in the brain. (A) Microgliosis in neocortex of APP/PS1 control mice; (B) Scutellarin treated APP/PS1 transgenic mice; (C) Wild-type control mice; (D) Comparison of CD45 area fraction in neocortex and hippocampus among groups. Scutellarin significantly decreased the number of microgliosis in the brain of treated mice. * p < 0.05 versus APP/PS1 transgenic mice. Scalebar = 0.5 mm. Original magnification, 4×.
