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. 2018 Mar 9;23(3):622. doi: 10.3390/molecules23030622

Table 1.

Types of dendrimers, with the nature and number of their terminal functions, used for comparison in different biological experiments. The most efficient compound for each experiment is highlighted in red.

PPH PAMAM PPI PCSi P-Lys Experiment Ref.
-NEt2H)96 -NH3)64 -NMe3)24 Clinical tests [35]
-NEt2H)96 -NH3)64 Transfection [37]
-NEt2H)48/
-NEt2H)96
-NH3)32/
-NH3)64
-NMe3)8 Protection SiRNA 1 [38]
-NEt2H)48/
-NEt2H)96
-NH3)32/
-NH3)64
-NMe3)8 Carrier of Si RNA [39]
-NEt2H)96 -NH3)64/
-NH3)128
-NH3)16 Peptide aggregation scavenger [40]
-NEt2H)96 -NH3)64/
-NH3)128
-NH3)16 Interaction with heparin [41]
-NEt2H)48/
-NEt2H)96
-NH3)32/
-NH3)64
Decrease ROS 2 levels [44]
(PO3HNa)2]12 (PO3HNa)2]8 Against RA 3 [53]
(PO3HNa)2]12 4 (PO3HNa)2]8 (PO3HNa)2]8 (PO3HNa)2]8 (PO3HNa)2]8 Activation of monocytes [54]

1 Small interfering RNA. 2 Reactive Oxygen Species. 3 Rheumatoid Arthritis. 4 Same efficiency with PPH (PO3HNa)2]8 [50].