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The factors and response values of response surface method.
| No. | X1/mL·g−1 | X2/% | X3/h | Y (IC50 (μg/mL)) |
|---|---|---|---|---|
| 1 | 1 | 0 | 1 | 218.55 |
| 2 | 0 | 0 | 0 | 205.04 |
| 3 | 0 | 0 | 0 | 205.09 |
| 4 | 0 | 0 | 0 | 208.40 |
| 5 | 0 | 1 | −1 | 338.87 |
| 6 | 0 | −1 | −1 | 382.21 |
| 7 | 0 | −1 | 1 | 257.91 |
| 8 | −1 | −1 | 0 | 208.50 |
| 9 | 0 | 0 | 0 | 202.47 |
| 10 | 1 | −1 | 0 | 312.52 |
| 11 | 0 | 0 | 0 | 204.07 |
| 12 | 1 | 1 | 0 | 321.01 |
| 13 | −1 | 0 | −1 | 197.13 |
| 14 | 0 | 1 | 1 | 473.46 |
| 15 | −1 | 1 | 0 | 372.92 |
| 16 | −1 | 0 | 1 | 216.58 |
| 17 | 1 | 0 | −1 | 231.38 |
