Table 3.

Cytotoxic activities of compounds 1–5.

Cell Lines	Cytotoxicity IC50 (μg/mL)
	1	2	3	4	5	Epothilon B
L929	28	45	40	45	40	0.0014
KB3.1	19	39	35	39	33	0.00022
A431	22	-	27	21	14	0.0006
A549	nt	-	70	52	43	0.005
PC-3	8	-	45	40	39	0.0002
SKOV-3	26	-	38	36	34	0.0014
MCF-7	20	-	18	17	16	0.0004

Not active, nt- not tested.