Table 3.

The drug-specific AUEC separated by positive and negative AUEC for each group (mean ± SE, n = 5).

Group	Formulation	Routes	Animals	Positive AUEC	Negative AUEC
1	Leuprolide solution	IV	Wistar	208.24 ± 52.30	−1404.30 ± 287.31 *
3		SC	Wistar	220.87 ± 39.56	−775.98 ± 289.13 *
4	SR depot	SC	Wistar	407.91 ± 111.95	−761.48 ± 292.02 *
6		SC	Iar:COP	354.12 ± 78.95	−880.28 ± 298.31 *

* p < 0.05 between positive and negative AUEC after administration of leuprolide.