Table 2.
Different types of PHA described in this review used for drug release studies.
| Type of PHA | Application | Ref. |
|---|---|---|
| Poly(3-hydroxybutyrate) (PHB)(Homopolyester; scl-PHA) | Release of rifampicin immobilized in PHA microspheres | [57] |
| Sustained rhodamine B isothiocyanate release by macrophage endocytosis | [59] | |
| Nanofibrous scaffolds for kanamycin release to prevent infection by Staphylococcus aureus | [60] | |
| In-colon delivery of the anticancer drug 5-fluorouracil from PHB/cellulose acetate phthalate microspheres prepared by solvent casting | [64] | |
| Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBHV)(Copolyester; scl-PHA) | Release of tetracycline immobilized in PHBHV microspheres and microcapsules | [58] |
| PHBHV rods loaded with sulbactam:cefoperazone and gentamicin for sustained antibiotic release | [61] | |
| PHBHV/PVA nanospheres for in-colon delivery of the anticancer drug 5-fluorouracil | [64] | |
| PHBHV/PVA nanospheres loaded with fingolimod to treat multiple sclerosis | [54] | |
| PHBHV nanospheres coated with PVA for release of antineoplastic drug ellipticine (cancer therapy) | [65] | |
| Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (PHB4HB)(Copolyester; scl-PHA) | Local release of antibiotics Sulperazone® and Duocid® for treatment of chronic osteomyelitis | [62] |
| Microspheres loaded with the phytoestrogen daidzein prepared by electrospraying for osteoporosis hormone therapy | [63] | |
| Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx)(Copolyester; scl-mcl-PHA) | Sustained rhodamine B isothiocyanate release by macrophage endocytosis | [59] |
| Rhodamine-B-loaded PHBHHx nanoparticles coated with poly(ethylene imine) to study ex vivo and in vivo cell response | [66] | |
| Poly(3-hydroxyoctanoate) (PHO)(Homopolyester; scl-PHA) | Biocompatibility studies with NG108-15 neuronal cells for nerve tissue engineering | [52] |