. 2018 Feb 6;23(2):340. doi: 10.3390/molecules23020340

Table 1.

Preliminary screening (Efficacy, maximal response) and GPR40 agonistic activities (Potency, EC₅₀) of compounds 1–5 in calcium assay for hGPR40/Gα16/HEK293.

Comp.	Maximal Response % (100 μM)	EC₅₀ (μM) ^a
1	98 ± 10	0.075 ± 0.02
2	103 ± 3	0.648 ± 0.10
3	105 ± 15	0.797 ± 0.17
4	84	≈100
5	9.9	>100
LA	100	8.30 ± 1.7

^a Means of two experiments.