Figure 3.

Amyloid biomarkers as target molecules for diagnostic methods and therapeutic approaches in conformational diseases. If we open the amyloid biomarker nucleus we will find several polymorphic amyloid molecules of different target proteins such as APP, AB, amylin, etc. These polymorphic amyloid molecules lead developing actions for diagnostic methods such immunoassays (ELISA, WB, immunodot, etc.), PET/SPECT with several reagents. In relation of multi-target therapeutic drugs, the main explored therapeutic approach is the use of chemical chaperones.