Table 4.

Stratification analysis of rs1412125 polymorphisms and risk of lung cancer.

Variables	Genotype	Cases (%)	Controls (%)	OR (95%CI) *	p-Value
Smoking-no	TT	339 (60.0%)	276 (52.9%)	1
	CT	199 (35.2%)	215 (41.2%)	0.756 (0.589, 0.971)	0.028
	CC	27 (4.8%)	31 (5.8%)	0.709 (0.413, 1.217)	0.213
	Dominant model
	TT	339 (60.0%)	276 (52.9%)	1	0.019
	CT + CC	226 (40.0%)	246 (47.1%)	0.750 (0.589, 0.954)
	Recessive model
	TT + CT	538 (95.2%)	491 (94.1%)	1	0.393
	CC	27 (4.8%)	31 (5.9%)	0.794 (0.467, 1.349)
Smoking-yes	TT	141 (58.5%)	41 (50.0%)	1
	CT	87 (36.1%)	34 (41.5%)	0.756 (0.441, 1.296)	0.308
	CC	13 (5.4%)	7 (8.5%)	0.518 (0.192, 1.399)	0.194
	Dominant model
	TT	141 (58.5%)	41 (50.0%)	1	0.198
	CT + CC	100 (41.5%)	41 (50.0%)	0.713 (0.427, 1.192)
	Recessive model
	TT + CT	228 (94.6%)	75 (91.5%)	1	0.272
	CC	13 (5.4%)	7 (8.5%)	0.582 (0.222, 1.529)
Gender-male	TT	127 (58.8%)	49 (52.7%)	1
	CT	77 (35.6%)	36 (38.7%)	0.848 (0.492, 1.462)	0.553
	CC	12 (5.6%)	8 (8.6%)	0.492 (0.176, 1.373)	0.175
	Dominant model
	TT	127 (58.8%)	49 (52.7%)	1	0.350
	CT + CC	89 (41.2%)	44 (47.3%)	0.781 (0.466, 1.311)
	Recessive model
	TT + CT	204 (94.4%)	85 (91.4%)	1	0.208
	CC	12 (5.6%)	8 (8.6%)	0.526 (0.193, 1.431)
Gender-female	TT	384 (60.6%)	341 (54.2%)	1
	CT	219 (34.5%)	254 (39.7%)	0.727 (0.573, 0.922)	0.009
	CC	31 (4.9%)	39 (6.1%)	0.709 (0.427, 1.176)	0.182
	Dominant model
	TT	384 (60.6%)	347 (54.2%)	1	0.006
	CT + CC	250 (39.4%)	293 (45.8%)	0.725 (0.577, 0.911)
	Recessive model
	TT + CT	603 (95.1%)	601 (93.9%)	1	0.388
	CC	31 (4.9%)	39 (6.1%)	0.804 (0.489, 1.321)

OR, Odd ratio; 95% CI, 95% Confident Interval; * OR was adjusted by age, gender and smoking.