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. 2018 Mar 21;23(4):718. doi: 10.3390/molecules23040718
AD Alzheimer’s disease
Abeta
APP β-amyloid precursor protein
MALDI-TOF Matrix-assisted-laser-desorption ionization time-of-flight
pyroGlu-3, AβpE3-x pyroglutamate Abeta starting with position 3
Asp-1 Abeta starting with aspartate at position 1
Ala-2 Abeta starting with alanine at position 2
Phe-4 Abeta starting with phenylalanine at position 4
Arg-5 Abeta starting with arginine at position 5
fEPSP field excitatory postsynaptic potential
PPF paired-pulse facilitation
Ca2+ calcium 2+
PTP post-tetanic potentiation
STP short-term potentiation
LTP long-term potentiation
NMDA N-methyl-D-aspartate
RM-ANOVA repeated measures ANOVA
WT wildtype
IO curve input–output curve
PS1 presenilin-1
Swe Swedish
Flo Florida
Lon London
Ind Indiana
m age in months
n.a. not analyzed
decreased
increased
sec seconds
min minutes