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. 2018 Mar 2;23(3):567. doi: 10.3390/molecules23030567

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Activity of DC-S285 and of ligand observed 1D NMR experiments. (A,B). Inhibitory activities of DC-S285 and its reference compound SAH based on the AlphaLISA assay; (C). Carr-Purcell Meiboom-Gill Pulse Sequence reveals that DC-S285 binds to SET7. T1ρ spectra acquired by using DC-S285 (colored in red), 20 μM DC-S285 in the presence of 2.5 μM protein (coloured in blue).